Richardson-Whitfield is best known for her role as Dr. Allison Blake in the Syfy television series Eureka (2006-2012) and has also guest-starred in other popular shows such as Stargate SG-1, CSI: Miami, NYPD Blue (with Gordon Clapp), Bones, and House M.D.. She most recently appeared in I am Legend, co-starring with Will Smith. She played Elizabeth Watts in an episode of Castle, the sister of Victoria Gates, played by Penny Johnson.