USCGC Sagebrush (WLB-399) was a USCG seagoing buoy tender. An Iris class vessel, she was built by Zenith Dredge Corporation. On 15 July 1943 the keel was laid; she was launched on 30 September 1943 and commissioned on 1 April 1944. She was decommissioned on 26 April 1988 and scuttled on 28 April 1988.