The Battle of the Sesia or Battle of the Sesia River, took place near the Sesia River (Latin: Sesites or Sessite), situated in north-western Italy, Lombardy, on 30 April 1524, between the Spanish-Imperial forces commanded by Don Carlos de Lannoy, inflicted a decisive defeat to the French forces under the Admiral Guillaume Gouffier, Lord of Bonnivet and Francis de Bourbon, Comte de St. Pol, during the Italian War of 1521–1526.