Matthew O'Donnell (born March 26, 1989 in Comox, British Columbia) is an American football offensive lineman who is currently a free agent. O'Donnell played high school football at Holy Cross Catholic Secondary School in Kingston Ontario. In the Canadian Football League's Amateur Scouting Bureau final rankings, he was ranked as the 11th best player for players eligible in the 2011 CFL Draft, and sixth by players in the CIS. On December 17, 2010, it was announced that O'Donnell was one of two CIS players to be named to the East–West Shrine Game.