The "hopping cough" is a disease that the Smurfs caught in the cartoon show episode "Hopping Cough Smurfs". It was created by Gargamel in one of his attempts to catch and destroy the Smurfs. The disease causes whoever catches it to cough and hop with each cough. It is said to be a deadly disease, though the episode never explains how that is the case. It is most likely meant that the disease would be incurable if it is not cured before sundown. Papa Smurf says that the cure for the "hopping cough" requires penicillium mold from the Mold Mines, steam from the Demon Springs, and the tail feather of the hopping crane, which when mixed together is administered through a vaccination shot right in the behind.
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