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| - Rosetta@home is a Distributed computing project for protein structure prediction on the Berkeley Open Infrastructure for Network Computing (BOINC) platform, run by the David Baker (biochemist) at the University of Washington. Rosetta@home also aims to predict protein-protein docking and design new proteins with the help of over 86,000 volunteered computers processing over 77 teraFLOPS on average as of November 30, 2008. Though much of the project is oriented towards basic research on improving the accuracy and robustness of the proteomics methods, Rosetta@home also does applied research on Malaria, Alzheimer's disease and other pathologies.
- Rosetta is a distributed computing project using the Boinc platform. This platform allows volunteers to download client software which will run on their computer, and depending on settings will run at all time, or while the computer is turned on but not in use to participate in scientific projects. Rosetta@Home is one such project which uses volunteers computers distributed throughout the world, connected via the internet to predict protein structures. If you wish to participate in Boinc projects, you may download the software from the official site. Boinc Site
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| abstract
| - Rosetta@home is a Distributed computing project for protein structure prediction on the Berkeley Open Infrastructure for Network Computing (BOINC) platform, run by the David Baker (biochemist) at the University of Washington. Rosetta@home also aims to predict protein-protein docking and design new proteins with the help of over 86,000 volunteered computers processing over 77 teraFLOPS on average as of November 30, 2008. Though much of the project is oriented towards basic research on improving the accuracy and robustness of the proteomics methods, Rosetta@home also does applied research on Malaria, Alzheimer's disease and other pathologies. Like all BOINC projects, Rosetta@home uses idle computer processing resources from volunteers' computers to perform calculations on individual workunits. Completed results are sent to a central project server where they are validated and assimilated into project Databases. The project is Cross-platform, and runs on a wide variety of Hardware configurations. Users can view the progress of their individual protein structure prediction on the Rosetta@home screensaver. In addition to disease-related research, the Rosetta@home network serves as a testing framework for new methods in structural bioinformatics. These new methods are then used in other Rosetta-based applications, like RosettaDock and the Human Proteome Folding Project, after being sufficiently developed and proven stable on Rosetta@home's large and diverse collection of volunteer computers. Two particularly important tests for the new methods developed in Rosetta@home are the Critical Assessment of Techniques for Protein Structure Prediction (CASP) and Critical Assessment of Prediction of Interactions (CAPRI) experiments, biannual experiments which evaluate the state of the art in protein structure prediction and protein-protein docking prediction, respectively. Rosetta@home consistently ranks among the foremost docking predictors, and is one of the best tertiary structure predictors available.
- Rosetta is a distributed computing project using the Boinc platform. This platform allows volunteers to download client software which will run on their computer, and depending on settings will run at all time, or while the computer is turned on but not in use to participate in scientific projects. Rosetta@Home is one such project which uses volunteers computers distributed throughout the world, connected via the internet to predict protein structures. The Rosetta system is used in FoldIt, which has thus far proven to be one of the most accurate methods of protein structure prediction through computer simulation. More information may be found at the Rosetta@Home website. If you wish to participate in Boinc projects, you may download the software from the official site. Boinc Site If you feel the Boinc software may be too complicated, or do not wish to spend as long configuring and choosing projects, another great site which offers access to these projects, and an online tool to manage participation is: Grid Republic
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