About: Alpha 1-antitrypsin deficiency   Sponge Permalink

An Entity of Type : owl:Thing, within Data Space : dbkwik.org associated with source dataset(s)

Symptoms are made worse if the lungs or liver are placed under unusual stress, such as smoking or drinking alcohol. Alpha 1-antitrypsin deficiency is a zebra diagnosis as it's primary symptom, difficulty breathing with unsual lung sounds, are a symptom of many more common lung conditions. In addition, Alpha 1-antitrypsin deficiency often is found together with other conditions such as COPD and cirrhosis which can arise alongside normal risk factors that exacerbate the symptoms of the condition. Diagnosis can usually be confirmed by testing Alpha 1-antitrypsin levels, which will be unusually low.

AttributesValues
rdfs:label
  • Alpha 1-antitrypsin deficiency
rdfs:comment
  • Symptoms are made worse if the lungs or liver are placed under unusual stress, such as smoking or drinking alcohol. Alpha 1-antitrypsin deficiency is a zebra diagnosis as it's primary symptom, difficulty breathing with unsual lung sounds, are a symptom of many more common lung conditions. In addition, Alpha 1-antitrypsin deficiency often is found together with other conditions such as COPD and cirrhosis which can arise alongside normal risk factors that exacerbate the symptoms of the condition. Diagnosis can usually be confirmed by testing Alpha 1-antitrypsin levels, which will be unusually low.
sameAs
dcterms:subject
mortalityrate
  • Moderate over the long term
symptom
  • Shortness of breath, wheezing, coarse lung sounds, crackling sound in stethoscope
dbkwik:house/prope...iPageUsesTemplate
Name
  • Alpha 1-antitrypsin deficiency
Type
treatment
  • Avoidance of smoke, intravenous alpha 1-antitrypsin
Cause
  • Lack of a protein which protects against inflammation, particularly in the lungs
abstract
  • Symptoms are made worse if the lungs or liver are placed under unusual stress, such as smoking or drinking alcohol. Alpha 1-antitrypsin deficiency is a zebra diagnosis as it's primary symptom, difficulty breathing with unsual lung sounds, are a symptom of many more common lung conditions. In addition, Alpha 1-antitrypsin deficiency often is found together with other conditions such as COPD and cirrhosis which can arise alongside normal risk factors that exacerbate the symptoms of the condition. Diagnosis can usually be confirmed by testing Alpha 1-antitrypsin levels, which will be unusually low. Most patients respond well to environmental and lifestyle changes. However, in more developed countries, patients are also given Alpha 1-antitrypsin derived from blood plasma. Alpha 1-antitrypsin deficiency is usually suggested by Robert Chase.
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