About: LE Prep   Sponge Permalink

An Entity of Type : owl:Thing, within Data Space : dbkwik.org associated with source dataset(s)

An LE prep (lupus erythematosus preparation) is medical test where blood is taken out of the patient, agitated (usually with small glass beads) and left to stand. Damaged cells will release their nuclei, which get coated with anti-nuclear antibodies (if present, as in the case of lupus or other autoimmune dieases). A blue dye is put in so that the clumpted nuclei are stained blue. These clumps are subsequently phagocytosed by Fc-bearing intact monocytes and neutrophils, which produces blue-stained monocytes and neutrophils (the LE cells). The test is positive in 70-90% of SLE patients.

AttributesValues
rdfs:label
  • LE Prep
rdfs:comment
  • An LE prep (lupus erythematosus preparation) is medical test where blood is taken out of the patient, agitated (usually with small glass beads) and left to stand. Damaged cells will release their nuclei, which get coated with anti-nuclear antibodies (if present, as in the case of lupus or other autoimmune dieases). A blue dye is put in so that the clumpted nuclei are stained blue. These clumps are subsequently phagocytosed by Fc-bearing intact monocytes and neutrophils, which produces blue-stained monocytes and neutrophils (the LE cells). The test is positive in 70-90% of SLE patients.
dcterms:subject
abstract
  • An LE prep (lupus erythematosus preparation) is medical test where blood is taken out of the patient, agitated (usually with small glass beads) and left to stand. Damaged cells will release their nuclei, which get coated with anti-nuclear antibodies (if present, as in the case of lupus or other autoimmune dieases). A blue dye is put in so that the clumpted nuclei are stained blue. These clumps are subsequently phagocytosed by Fc-bearing intact monocytes and neutrophils, which produces blue-stained monocytes and neutrophils (the LE cells). The test is positive in 70-90% of SLE patients. LE prep has largely been replaced by the more sensitive ANA titers.
Alternative Linked Data Views: ODE     Raw Data in: CXML | CSV | RDF ( N-Triples N3/Turtle JSON XML ) | OData ( Atom JSON ) | Microdata ( JSON HTML) | JSON-LD    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3217, on Linux (x86_64-pc-linux-gnu), Standard Edition
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2012 OpenLink Software