Belushi plays bad-tempered San Diego police detective Michael Dooley, who has been tagged for execution by a major international drug dealer named Lyman (played by Kevin Tighe). To help, K-9 Sergeant Brannigan (played by Ed O'Neill) gives Dooley an unorthodox drug-sniffing police dog called "Jerry Lee" (named after rock-and-roll singer Jerry Lee Lewis). The duo attempt to put Lyman in prison but Dooley soon learns that Jerry Lee is a mischievous smart aleck who works only when and how he wants to. Many of the movie's gags revolve around Jerry Lee's playfully destructive episodes.
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