About: Interview: Aubrey de Grey

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Interview with Aubrey de Grey by Jonathan Despres. Go to the Interviews. My original training was in computer science, but I've worked on aging for about ten years. My main project is "Strategies for Engineered Negligible Senescence" (SENS), a multi-part scheme to postpone aging indefinitely. My main goal is to demonstrate the feasibility of SENS by achieving what I call "Robust Mouse Rejuvenation" (RMR) -- reproducibly trebling the remaining lifespan of naturally long-lived (three years average lifespan) mice with therapies begun when they are already two.

Attributes	Values
rdfs:label	Interview: Aubrey de Grey
rdfs:comment	Interview with Aubrey de Grey by Jonathan Despres. Go to the Interviews. My original training was in computer science, but I've worked on aging for about ten years. My main project is "Strategies for Engineered Negligible Senescence" (SENS), a multi-part scheme to postpone aging indefinitely. My main goal is to demonstrate the feasibility of SENS by achieving what I call "Robust Mouse Rejuvenation" (RMR) -- reproducibly trebling the remaining lifespan of naturally long-lived (three years average lifespan) mice with therapies begun when they are already two.
dcterms:subject	Interview
abstract	Interview with Aubrey de Grey by Jonathan Despres. Go to the Interviews. My original training was in computer science, but I've worked on aging for about ten years. My main project is "Strategies for Engineered Negligible Senescence" (SENS), a multi-part scheme to postpone aging indefinitely. My main goal is to demonstrate the feasibility of SENS by achieving what I call "Robust Mouse Rejuvenation" (RMR) -- reproducibly trebling the remaining lifespan of naturally long-lived (three years average lifespan) mice with therapies begun when they are already two. In humans? I think that if both the money and the science go as well as they should, we have a 50% chance of getting "robust human rejuvenation" by 2030. That means giving typical 55-year-olds 30 extra healthy years. I think people who are cryopreserved with the best technology available today have a good chance of being revived with good fidelity, yes. I do not have a good estimate of how soon they will be revived, nor how they will be revived (e.g., whether by warming up the preserved body or by scanning it and building a new one from the information). Everything. I think biotechnology will extend lives before nanotech is far enough advanced, but I could be wrong - we need to keep all our options open. I'm not really driven by the idea of living an extremely long life (though I wouldn't object!) -- mainly what drives me is that I want to let people avoid getting frail and senile and decrepit and dependent as they get older. That seems obviously a desirable goal - I've always known it, so I can't point to a particular event that attracted me to it. No idea. I have no commercial expertise. Well, there are things that no one tries to do today because there isn't time, like travelling to the stars -- lots of people give that as a big reason why they want to live much longer. But also, very long projects of many other sorts. Fermat might have really proved his theorem before Wiles if he'd had all the intervening time available... Rich Miller. He's a senior biogerontologist who is very keen to defeat aging and he's very good at expressing himself. He disagrees with me about how we might best achieve that goal (and how soon), but his heart is in the right place!

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