Enemies usually combine Disease with Poison and/or Sap which will eventually reduce character's hit-point to only 1/1 (in such state, character is not regarded as HP Critical). Disease is cured with a Vaccine, the White Magicks Cleanse, or a Remedy, provided the character has the license, Remedy Lore 3. Characters who are currently in Bubble status will be immune to Disease. A KO'd character with Disease status will have only 1/1 HP if he/she was revived. A character can inflict Disease on enemies by using Vaccine or Remedy only if that character has the accessory Nihopalaoa equipped.
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| - Enemies usually combine Disease with Poison and/or Sap which will eventually reduce character's hit-point to only 1/1 (in such state, character is not regarded as HP Critical). Disease is cured with a Vaccine, the White Magicks Cleanse, or a Remedy, provided the character has the license, Remedy Lore 3. Characters who are currently in Bubble status will be immune to Disease. A KO'd character with Disease status will have only 1/1 HP if he/she was revived. A character can inflict Disease on enemies by using Vaccine or Remedy only if that character has the accessory Nihopalaoa equipped.
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| - Enemies usually combine Disease with Poison and/or Sap which will eventually reduce character's hit-point to only 1/1 (in such state, character is not regarded as HP Critical). Disease is cured with a Vaccine, the White Magicks Cleanse, or a Remedy, provided the character has the license, Remedy Lore 3. Characters who are currently in Bubble status will be immune to Disease. A KO'd character with Disease status will have only 1/1 HP if he/she was revived. A character can inflict Disease on enemies by using Vaccine or Remedy only if that character has the accessory Nihopalaoa equipped. In the International Zodiac Job System version, a newly included mace "Guriguri Banban" can inflict Disease along with Sap while attacking with 100% success rate. It is a vital weapon for the 100th stage of the Trial Mode. It can also be inflicted upon one enemy using the offensive item Meteorite (B).
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