Thalidomide is a pharmaceutical sedative that was developed in the late 1950s as a seemingly safer alternative to barbituates. However, in pregnant women, thalidomide turned out to have a very large risk of birth defects, generally foreshortened arms and legs. Thousands of infants were born with these defects before thalidomide was identified as the culprit and taken off the marketplace in the early 1960s.
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