The 59th Virginia Volunteer Infantry Regiment was an infantry regiment raised in Virginia's western counties for service in the Confederate States Army during the American Civil War. It fought mostly with the Army of Northern Virginia, and in the Carolinas. The 59th Virginia (also called 2nd Regiment, Wise Legion) was organized in August 1861. Part of this unit was captured at Roanoke Island in February 1862. Four of the companies were not captured and reorganized into the 26th Virginia Infantry Battalion.