The USS Ganges (NCC-72454) was a Danube-class runabout serving in the 24th century and assigned to Deep Space 9 after being dropped off there in 2369 by the USS Enterprise-D. The Ganges was outfitted with a special mission module when it aided in the arrest of the Bajoran terrorist Tahna Los. It also picked up the stranded scientist Vash on a routine mission to the Gamma Quadrant and then suffered a mysterious power loss on the return trip to the station. In 2370, the Ganges was the last ship to evacuate from Deep Space Nine after the attempted coup on Bajor.
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