USS Key West (1862) was a steamer acquired by the Union Navy during the American Civil War. She was used by the Union Navy as a convoy and patrol vessel on Confederate waterways, only to be sunk, along with Elfin and Tawah by Confederate shore batteries. Key West was built in 1862 at California, Pennsylvania, as Key West No. 8; purchased by the Navy from W. S. Evans et al. at Cairo, Illinois, 16 April 1863; and commissioned 26 May, Acting Master E. M. King in command.