Adrian E. Regnier (August 28, 1889 – March 2, 1956) was an American football player and coach. He played college football at Brown University at the halfback and end positions from 1907 to 1909. He was the captain of the 1909 Brown Bears football team and was selected as a consensus All-American at the end position in 1909. Regnier also played baseball and basketball and was a member of the Phi Delta Theta fraternity. He graduated from Brown in 1910.