HMS Southampton was the name ship of the 32-gun Southampton-class fifth-rate frigates of the Royal Navy. She was launched in 1757 and served for more than half a century until wrecked in 1812. On 3 August 1780, Southampton captured the French privateer lugger Comte de Maurepas, of 12 guns and 80 men, under the command of Joseph Le Cluck. She had on board Mr. Andrew Stuart, Surgeon's Mate of HMS Speedwell, "as a ransomer." She had suffered shot holes between wind and water and sank shortly thereafter. Southampton shared the head money award with Buffalo, Thetis, and Alarm.