Leslie Sears (joined Caduceus in 2012), is one of Caduceus' nurses featured in Trauma Center: Under the Knife, Under the Knife 2, and Second Opinion. She is almost always upbeat and jovial. Her positive attitude filters throughout the hospital, making her a popular nurse among patients. She spends a lot of her time helping Dr. Chase, and she continues to help him in Under the Knife 2. She has also looked after Dr. Chase's sister, Amy.