Frank Cosentino (born May 22, 1937) was a quarterback in the Canadian Football League. Cosentino was a graduate of the University of Western Ontario, where he captained the football team to the first Canadian Interuniversity Sport championship in 1959. As a professional he played for the Hamilton Tiger-Cats, Edmonton Eskimos and the Toronto Argonauts of the CFL from 1960 to 1969. Cosentino's career was noteworthy in that he was one of the last Canadian quarterbacks to see significant playing time in the CFL.