The film opens with an outbreak of the T-virus in Shibuya, Tokyo, taking place concurrently with the Raccoon City Incident. Four years later, it has since been repurposed as the global headquarters of the Umbrella Corporation taking refuge under it, with snipers positioned on building roofs to keep the Undead from breaching the expansive underground facility. Living up to her threat made in Extinction, Alice and her clones travel to Tokyo to take out Umbrella's chairman, Albert Wesker. They break into the underground base, with one clone dispatching a number of guards in anticipation of the rest of the Alice clones' arrival. The clones storm the facility and kill a large number of Umbrella soldiers. The real Alice goes after Wesker, following him onto a V-22 Osprey as he prepares to detona