Irene Manning (previously Lord and Clayton is a fictional character from the original daytime soap opera, One Life to Live. The character first appears on-screen in July 1978 being portrayed by actress, Kate McKeown. In 1985, Andrea Evans, the actress who played Irene's daughter Tina Lord would take over the role in flashback. Actress Diana Lamar would appear as Irene during the 1994 storyline which revealed Irene and Victor's secret son, Todd Manning. Veteran actress, Barbara Rhoades first appears as Irene on August 9, 2011.