At least one universe existed before the one the Doctor lived in. (PROSE: The Pit, PROSE: Millennial Rites, TV: Secrets of the Stars) The Great Old Ones, the Beast, and the Disciples of the Light, natives of this pre-universe, survived the Big Bang. (PROSE: The Quantum Archangel, TV: The Impossible Planet) The Ancient Lights continued some sort of existence after Event One, but was unable to enter the new universe. (TV: Secrets of the Stars)