The RG7421 has a fixed bridge and dual Ibanez humbucker pickups. The body was originally basswood, but it was changed to mahogany for 2015. A similar model with a tremolo bridge is the RG7420. A version with an exotic poplar burl top, the RG7421PB, is also offered. A guitar with the same model number was a previously available between 2000 and 2003.