Martha was a mutant runaway who was captured by the human supremacist group, the U-Men. Their founder John Sublime had her brain removed from her body, keeping the disembodied brain alive in a capsule. She has the power to negate any mutant's powers, like Leech. Sublime controlled her through drugs and syringes and used her to subdue his opponents, the two X-Men, Cyclops and Emma Frost. The two X-Men eventually broke free of her control, after which Martha took her revenge on Sublime by causing him to fall to his death. She later became a student in the Xavier Institute's Special Class. Quentin Quire invented a special hovering case to hold her brain, usually linked to a chain held by Ernst, a mysterious, super-strong mutant appearing like an old woman, who often repeated Martha's telepath