Initial effect: Lowers strength by 2 to 16 (2d8). Secondary effect: Lowers strength by 2 to 16 (2d8). Save DC: 35 Colossal spider venom is resisted upon contraction if the target makes a successful fortitude saving throw. If the save fails, the initial effect is applied, and one minute later a second saving throw is attempted to avoid the secondary effect.
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